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Article

Differentially Regulated Genes as Putative Targets of Amplifications at 20q in Ovarian Cancers

1 Oct 2002

Abstract excerpt

Frequent amplification of DNA at 20q or part of 20q has been demonstrated by comparative genomic hybridization in ovarian cancer (OC), but the genetic target(s) of these amplification events remain unknown. We examined copy-number changes with respect to six candidate genes, E2F1 (20q11.2), TGIF2 (20q11.2), AIB1 (20q12), PTPN1 (20q13.1), ZNF217 (20q13.2), and BTAK (20q13), and then measured transcription levels...

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Identifiers

PMID: 12417041
DOI: 10.1111/j.1349-7006.2002.tb01213.x

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