Article
Mapping of chromosomal imbalances in gastric adenocarcinoma revealed amplified protooncogenes <i>MYCN</i> , <i>MET</i> , <i>WNT2</i> , and <i>ERBB2</i>
1 Dec 1998
Abstract excerpt
Gastric adenocarcinoma is a malignant tumor with a high incidence and a low survival rate. In order to identify genetic alterations associated with this tumor, we screened 23 gastric adenocarcinomas for recurrent chromosomal imbalances by using comparative genomic hybridization (CGH). The most common gains of chromosomal material were found on chromosome arms 20q (10 cases), 16p (7 cases), and 1q (4 cases) and on...
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