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High resolution analysis of DNA copy-number aberrations of chromosomes 8, 13, and 20 in gastric cancers

20 Aug 2009

Abstract excerpt

DNA copy-number gains of chromosomes 8q, 13q, and 20q are frequently observed in gastric cancers. Moreover gain of chromosome 20q has been associated with lymph node metastasis. The aim of this study was to correlate DNA copy-number changes of individual genes on chromosomes 8q, 13q, and 20q in gastric adenocarcinomas to clinicopathological data. DNA isolated from 63 formalin-fixed and paraffin-embedded gastric...

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PMID: 19697059
DOI: 10.1007/s00428-009-0814-y

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