Article
Palmitoylation of the murine leukemia virus envelope protein is critical for lipid raft association and surface expression.
Journal of virology - 1 Dec 2002
Li Min, Yang Chinglai, Tong Suxiang, Weidmann Armin, Compans Richard W
Abstract excerpt
To investigate the association of the murine leukemia virus (MuLV) Env protein with lipid rafts, we compared wild-type and palmitoylation-deficient mutant Env proteins by using extraction with the mild detergent Triton X-100 (TX-100) followed by a sucrose gradient flotation assay. We found that the wild-type MuLV Env protein was resistant to ice-cold TX-100 treatment and floated to the top of the gradients. In...
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