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Article

Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion.

Proceedings of the National Academy of Sciences of the United States of America - 9 Dec 2003

Takeda Makoto, Leser George P, Russell Charles J, Lamb Robert A

Abstract excerpt

Lipid raft microdomains are enriched in sphingomyelin and cholesterol and function as platforms for signal transduction and as the site of budding of several enveloped viruses, including influenza virus. The influenza virus hemagglutinin (HA) glycoprotein, which mediates both viral-cell attachment and membrane fusion, associates intrinsically with lipid rafts. Residues in the HA transmembrane (TM) domain are...

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Identifiers

PMID: 14561897
DOI: 10.1073/pnas.2235620100
PMCID: PMC299746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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