Article
Increasing acidification of nonreplicating Lactococcus lactis deltathyA mutants by incorporating ATPase activity.
Applied and environmental microbiology - 1 Nov 2002
Pedersen Martin B, Koebmann Brian J, Jensen Peter R, Nilsson Dan
Abstract excerpt
Lactococcus lactis MBP71 deltathyA (thymidylate synthase) cannot synthesize dTTP de novo, and DNA replication is dependent on thymidine in the growth medium. In the nonreplicating state acidification by MBP71 was completely insensitive to bacteriophages (M. B. Pedersen, P. R. Jensen, T. Janzen, and D. Nilsson, Appl. Environ. Microbiol. 68:3010-3023, 2002). For nonreplicating MBP71 the biomass increased 3.3-fold...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.