Article
Evaluation of the angiotensinogen locus in human essential hypertension: a European study.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 1998
Brand E, Chatelain N, Keavney B, Caulfield M, Citterio L, Connell J, Grobbee D, Schmidt S, Schunkert H, Schuster H, Sharma A M, Soubrier F
Abstract excerpt
Different family and case-control studies support genetic linkage and association at the human angiotensinogen (AGT) locus with essential hypertension. To extend these previous observations, a European collaborative study of nine centers was set up to create a large resource of affected sibling p...
Topics
- Adult
- Alleles
- Angiotensinogen
- Dinucleotide Repeats
- Europe
- Family
- Female
- Gene Frequency
- Genetic Linkage
- Humans
- Hypertension
- Male
- Microsatellite Repeats
- Middle Aged
- Polymorphism, Genetic