Article
The LDL receptor-related protein (LRP1/A2MR) and coronary atherosclerosis--novel genomic variants and functional consequences.
Human mutation - 1 Nov 2002
Schulz Susanne, Schagdarsurengin Undraga, Greiser Petra, Birkenmeier Gerd, Müller-Werdan Ursula, Hagemann Monika, Riemann Dagmar, Werdan Karl, Gläser Christiane
Abstract excerpt
The LDL receptor-related protein/alpha 2-macroglobulin receptor (LRP1/A2MR) is a multifunctional cell-surface glycoprotein that endocytoses several structurally and functionally distinct ligands. In clinical studies different genomic variants of the LRP1/A2MR and its role in the development of degenerative diseases like atherosclerosis or Alzheimer's disease were studied. We screened for novel genomic variants of...
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