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Article

Phenotypes of lexA mutations in Salmonella enterica: evidence for a lethal lexA null phenotype due to the Fels-2 prophage.

Journal of bacteriology - 1 Nov 2002

Bunny Kim, Liu Jing, Roth John

Abstract excerpt

The LexA protein of Escherichia coli represses the damage-inducible SOS regulon, which includes genes for repair of DNA. Surprisingly, lexA null mutations in Salmonella enterica are lethal even with a sulA mutation, which corrects lexA lethality in E. coli. Nine suppressors of lethality isolated in a sulA mutant of S. enterica had lost the Fels-2 prophage, and seven of these (which grew better) had also lost the...

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Share to Prophages
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to SOS Response, Genetics

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Identifiers

PMID: 12399494
DOI: 10.1128/JB.184.22.6235-6249.2002
PMCID: PMC151935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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