Article
Genetic variation in proinflammatory and anti-inflammatory cytokine production in multiple organ dysfunction syndrome.
Critical care medicine - 1 Oct 2002
Reid Clare L, Perrey Chris, Pravica Vera, Hutchinson Ian V, Campbell Iain T
Abstract excerpt
OBJECTIVES: The objectives of this study were to examine the prevalence of genetic variation for cytokine production (tumor necrosis factor [TNF]-alpha, interleukin-10, transforming growth factor-beta1) in patients with multiple organ dysfunction syndrome, to measure circulating cytokine levels and relate these to genotype, and to identify the relationship between genetic variation and outcome. DESIGN:...
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