Article
Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype.
Alcoholism, clinical and experimental research - 1 Oct 2002
Dick Danielle M, Nurnberger John, Edenberg Howard J, Goate Alison, Crowe Ray, Rice John, Bucholz Kathleen K, Kramer John, Schuckit Marc A, Smith Tom L, Porjesz Bernice, Begleiter Henri, Hesselbrock Victor, Foroud Tatiana
Abstract excerpt
BACKGROUND: Alcohol dependence is a clinically and etiologically heterogeneous disorder. Accordingly, a variety of subtypes of alcohol-dependent individuals have been proposed, and multiple operational definitions of alcohol use, abuse, and dependence have been used in linkage analyses directed toward detecting genes involved in alcohol use and problems. Here, we develop quantitative phenotypes that characterize...
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