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Article

Enamelysin (matrix metalloproteinase 20)-deficient mice display an amelogenesis imperfecta phenotype.

The Journal of biological chemistry - 20 Dec 2002

Caterina John J, Skobe Ziedonis, Shi Joanne, Ding Yanli, Simmer James P, Birkedal-Hansen Henning, Bartlett John D

Abstract excerpt

Enamelysin is a tooth-specific matrix metalloproteinase that is expressed during the early through middle stages of enamel development. The enamel matrix proteins amelogenin, ameloblastin, and enamelin are also expressed during this same approximate developmental time period, suggesting that enamelysin may play a role in their hydrolysis. In support of this interpretation, recombinant enamelysin was previously...

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Identifiers

PMID: 12393861
DOI: 10.1074/jbc.M209100200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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