MMP-20 mutation in autosomal recessive pigmented hypomaturation amelogenesis imperfecta

Abstract excerpt

During mammalian tooth formation, two proteinases are secreted by ameloblasts: enamelysin (MMP-20) and kallikrein-4 (KLK4). Enamelysin is the early protease. It is expressed by ameloblasts throughout the secretory stage and part of the maturation stage.1–3 KLK4 is the late protease; its expression by ameloblasts begins in the transition stage and continues throughout enamel maturation.4,5 Expression of these two...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone and Dental Protein Studies
• Share to dental development and anomalies
• Share to Periodontal Regeneration and Treatments