Article
Variants in the VCAM1 gene and risk for symptomatic stroke in sickle cell disease.
Blood - 15 Dec 2002
Taylor James G, Tang Delia C, Savage Sharon A, Leitman Susan F, Heller Seth I, Serjeant Graham R, Rodgers Griffin P, Chanock Stephen J
Abstract excerpt
Stroke is a major cause of morbidity and mortality in sickle cell (SS) disease. Genetic risk factors have been postulated to contribute to this clinical outcome. The human genome project has substantially increased the catalog of variations in genes, many of which could modify the risk for manifestations of disease outcome in a monogenic disease, namely SS. VCAM1 is a cell adhesion molecule postulated to play a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.