Article
Emergence of late cytomegalovirus central nervous system disease in hematopoietic stem cell transplant recipients.
Blood - 15 Jan 2003
Wolf Dana G, Lurain Nell S, Zuckerman Tsila, Hoffman Ron, Satinger Judith, Honigman Alik, Saleh Niveen, Robert Emanuel S, Rowe Jacob M, Kra-Oz Zipora
Abstract excerpt
Preemptive ganciclovir therapy has reduced the occurrence of early cytomegalovirus (CMV) disease after hematopoietic stem cell (HSC) transplantation. However, late disease is increasingly reported. We describe 2 patients who developed late CMV central nervous system (CNS) disease after haploidentical HSC transplantation. Direct genotypic analysis was used to examine the presence of ganciclovir resistance. One...
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