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Article

Susceptibility to lymphoid neoplasia in immunodeficient strains of nonobese diabetic mice.

Cancer research - 15 Oct 2002

Chiu Priscilla P L, Ivakine Evgueni, Mortin-Toth Steven, Danska Jayne S

Abstract excerpt

Transformed lymphocytes exhibit aberrant growth potential resulting from enhanced proliferation and resistance to apoptotic stimuli. These mechanisms also influence the development of autoimmune disease, where dysregulated lymphocyte homeostasis has been implicated in expansion of autoreactive T cells. In the nonobese diabetic (NOD) mouse, a murine model of autoimmune type 1 diabetes and Sjögren's syndrome, T...

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Source

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PMID: 12384545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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