Article
A pathogenic cytochrome b mutation reveals new interactions between subunits of the mitochondrial bc1 complex.
The Journal of biological chemistry - 20 Dec 2002
Saint-Georges Yann, Bonnefoy Nathalie, di Rago Jean Paul, Chiron Stephane, Dujardin Geneviève
Abstract excerpt
Energy transduction in mitochondria involves five oligomeric complexes embedded within the inner membrane. They are composed of catalytic and noncatalytic subunits, the role of these latter proteins often being difficult to assign. One of these complexes, the bc1 complex, is composed of three catalytic subunits including cytochrome b and seven or eight noncatalytic subunits. Recently, several mutations in the...
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