Article
Effects of mutations in mitochondrial cytochrome b in yeast and man. Deficiency, compensation and disease.
European journal of biochemistry - 1 Mar 2001
Fisher N, Meunier B
Abstract excerpt
The mitochondrial cytochrome bc(1) complex is a key protonmotive component of eukaryotic respiratory chains. The mitochondrially encoded cytochrome b forms, with cytochrome c(1) and the iron--sulfur protein, the catalytic core of this multimeric enzyme. Mutations of cytochrome b have been reported in association with human diseases. In the highly homologous yeast cytochrome b, several mutations that impair the...
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