Article
Functional mapping reveals the importance of yeast cytochrome b C-terminal region in assembly and function of the bc1 complex.
FEBS letters - 3 Mar 1997
Edderkaoui B, Meunier B, Colson-Corbisier A M
Abstract excerpt
Genetic and molecular analyses have been undertaken for four respiratory deficient mutants (mit-). The four mutations affect the C-terminal region of apocytochrome b. The frameshift (L263STOP) and non-sense (Q338STOP) mutations give rise to a truncated apocytochrome b. The mutant G337R conserves only 32% of its NADH oxidase activity which suggests that the presence of a positively charged amino acid in the...
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