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Article

An elevated mutation frequency favors development of vancomycin resistance in Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Nov 2002

Schaaff Franziska, Reipert Andrea, Bierbaum Gabriele

Abstract excerpt

The emergence of intermediate vancomycin resistance, mainly in methicillin-resistant Staphylococcus aureus strains, has become a great concern. Thorough characterization of clinical and laboratory vancomycin-intermediately resistant S. aureus (VISA) strains identified multiple, resistance-associated changes most probably due to stepwise mutations. We hypothesized that an elevated mutation frequency as found,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to MutS DNA Mismatch-Binding Protein

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Source

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Identifiers

PMID: 12384362
DOI: 10.1128/AAC.46.11.3540-3548.2002
PMCID: PMC128741

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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