Article
"Slow VISA," a novel phenotype of vancomycin resistance, found in vitro in heterogeneous vancomycin-intermediate Staphylococcus aureus strain Mu3.
Antimicrobial agents and chemotherapy - 1 Sept 2014
Saito Michie, Katayama Yuki, Hishinuma Tomomi, Iwamoto Akira, Aiba Yoshifumi, Kuwahara-Arai Kyoko, Cui Longzhu, Matsuo Miki, Aritaka Nanae, Hiramatsu Keiichi
Abstract excerpt
Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) clinical strain Mu3 spontaneously generates VISA strains at an extremely high frequency (≥1×10(-6)). The generated VISA strains usually grow more slowly than does the parent hVISA strain, but they form colonies on vancomycin-containing agar plates before 48 h of incubation. However, we noticed a curious group of VISA strains, designated "slow...
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