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Evaluation of Differential Gene Expression in Fluconazole-Susceptible and -Resistant Isolates of <i>Candida albicans</i> by cDNA Microarray Analysis

16 Oct 2002

Abstract excerpt

The opportunistic fungal pathogen Candida albicans is the major causative agent of oropharyngeal candidiasis (OPC) in AIDS. The development of azoles, such as fluconazole, for the treatment of OPC has proven effective except in cases where C. albicans develops resistance to fluconazole during the course of treatment. In the present study, we used microarray technology to examine differences in gene expression...

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PMID: 12384344
DOI: 10.1128/aac.46.11.3412-3417.2002

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