Article
Myofibroblast differentiation: plasma membrane microdomains and cell phenotype.
Experimental nephrology - 1 Jan 2002
Schelling Jeffery R, Sinha Sumita, Konieczkowski Martha, Sedor John R
Abstract excerpt
Myofibroblast differentiation characterizes a prominent cellular phenotype identified in experimental models of progressive kidney disease and human kidney biopsies. Mesangial cells, tubulointerstitial fibroblasts and, perhaps, tubular epithelial cells undergo myofibroblast differentiation, a process characterized by alpha-actin expression, synthesis of interstitial collagens and a growth response. Inhibition of...
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