Article
[Prevalence of hemochromatosis-associated mutations in the hemochromatosis gene in the Danish population].
Ugeskrift for laeger - 23 Sept 2002
Larsen Lisbeth Enggaard, Ellervik Christina, Appleyard Merete, Nordestgaard Børge G, Birgens Henrik, Tybjaerg-Hansen Anne
Abstract excerpt
INTRODUCTION: Hereditary haemochromatosis is an autosomal recessive condition characterised by systemic iron overload. In Northern Europe, 85-90% of patients with haemochromatosis are homozygous for the C282Y mutation in the HFE gene. In the present study, we determined the prevalence of the haemochromatosis-associated mutations, C282Y and H63D, in the Danish general population. MATERIAL AND METHODS: We genotyped...
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