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Article

Prevalence of C282Y and H63D mutations in the hemochromatosis (HFE) gene in the United States.

JAMA - 2 May 2001

Steinberg K K, Cogswell M E, Chang J C, Caudill S P, McQuillan G M, Bowman B A, Grummer-Strawn L M, Sampson E J, Khoury M J, Gallagher M L

Abstract excerpt

CONTEXT: Population-based estimates of the prevalence of disease-associated mutations, such as hemochromatosis (HFE) gene mutations, are needed to determine the usefulness of genetic screening. OBJECTIVE: To estimate the prevalence of the HFE mutations C282Y and H63D in the US population. DESIGN:...

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Share to Hemochromatosis
Share to Hemochromatosis Protein
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11325323
DOI: 10.1001/jama.285.17.2216

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11325323-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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