Article
[Molecular genetics of hemochromatosis].
Annales d'endocrinologie - 1 Sept 1999
David V, Jouanolle A M, Fergelot P, Brissot P, Deugnier Y, Le Gall J Y
Abstract excerpt
Hemochromatosis is a recessive disorder of iron metabolism characterized by progressive iron loading of parenchymal organs, which accounts for clinical complications such as cirrhosis, diabetes mellitus, cardiopathy, endocrine dysfunctions and arthropathy. Clinical complications, which usually develop after the third or fourth decade of life, can be fatal but may be prevented by phlebotomy if iron excess is...
Topics
- Genes, MHC Class I
- Genes, Recessive
- Hemochromatosis
- Humans
- Mutation