Article
Immortal phenotype of the esophageal epithelial cells in the process of immortalization.
International journal of molecular medicine - 1 Nov 2002
Shen Zhong-Ying, Xu Li-Yan, Li En-Min, Shen Jian, Zheng Rui-Ming, Cai Wei-Jia, Zeng Yi
Abstract excerpt
To search for potential biomarkers used to monitor the process of immortalization, we investigated the relative level of telomerase activity and other immortal phenotypes in the SHEE esophageal epithelial cell line. This human fetal esophageal epithelial cell line, induced by human papilloma virus (HPV) 18 E6E7, was continually propagated over 100 passages. Fourteenth passage cells (SHEE14) were cultured in a...
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