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Review of hTERT-Immortalized Cells: How to Assess Immortality and Confirm Identity

4 Dec 2024

Abstract excerpt

Cell immortalization has an important role in scientific research, as well as increasing significance in the context of cell therapy and biotechnology. Over the years, many immortalized cell lines have been produced using human telomerase reverse transcriptase (hTERT) alone or in a combination with viral oncogenes. Different hTERT-immortalized cells are commercially available, and numerous papers about obtaining...

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PMID: 39684765
DOI: 10.3390/ijms252313054

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