Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APC gene expression in gastric carcinoma: an immunohistochemical study.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Sept 2002

Grace A, Butler D, Gallagher M, Al-Agha R, Xin Y, Leader M, Kay E

Abstract excerpt

Gastric carcinoma is one of the most common malignancies worldwide, particularly in Japan and China. Inactivation of the adenomatous polyposis coli ( ) gene, a tumor suppressor gene, has been shown to play a significant role in the development of colorectal carcinoma, and it has been suggested that it may play a role throughout the digestive tract, including the stomach. This study assesses gene expression in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Adenomatous Polyposis Coli Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastric Mucosa

Share to Gene Expression

Share to Genes, APC

Share to Immunohistochemistry

Share to Mutation

Share to Stomach Neoplasms

Source

Identifiers

PMID: 12373147
DOI: 10.1097/00129039-200209000-00006

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APC gene expression in gastric carcinoma: an immunohistochemical study.PMID 12373147Read ↗

Monoallelic methylation of the APC promoter is altered in normal gastric mucosa associated with neoplastic lesions.Semantic proximity Read ↗

Low-grade gastric adenomas/dysplasias: phenotypic expression, DNA ploidy pattern, and LOH at microsatellites linked to the APC gene.Semantic proximity Read ↗

Severity of atrophic gastritis related to antiparietal cell antibody and gastric carcinogenesis, including p53 mutations.Semantic proximity Read ↗

Lack of mutations of the adenomatous polyposis coli gene in oesophageal and gastric carcinomas.Semantic proximity Read ↗

Intramucosal carcinomas of the stomach: phenotypic expression and loss of heterozygosity at microsatellites linked to the APC gene.Semantic proximity Read ↗

Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer.Semantic proximity Read ↗

Loss of heterozygosity and immunohistochemistry of adenocarcinomas of the esophagus and gastric cardia.Semantic proximity Read ↗

Mutations of the APC gene occur during early stages of gastric adenoma development.Semantic proximity Read ↗

Beta-catenin expression in intramucosal neoplastic lesions of the stomach. Comparative analysis of adenoma/dysplasia, adenocarcinoma and signet-ring cell carcinoma.Semantic proximity Read ↗

Deficiency of Adenomatous Polyposis Coli protein in sporadic colorectal adenomas and its associations with clinical phenotype and histology.Semantic proximity Read ↗

Loss of Beta-Catenin Expression in Metastatic Gastric CancerSemantic proximity Read ↗

Loss of SMAD4 function in small intestinal adenocarcinomas: comparison of genetic and immunohistochemical findings.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.