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Article

Effects of the osmolyte trimethylamine-N-oxide on conformation, self-association, and two-dimensional crystallization of myelin basic protein.

Journal of structural biology - 1 Jul 2002

Hill Christopher M, Bates Ian R, White Gisele F, Hallett F Ross, Harauz G

Abstract excerpt

The osmolyte trimethylamine-N-oxide (TMAO) is a naturally in vivo occurring "chemical chaperone" that has been shown to stabilise the folding of numerous proteins. Myelin basic protein (MBP) is a molecule that has not yet been suitably crystallized either in three dimensions for X-ray crystallogr...

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Source

Identifiers

PMID: 12372316
DOI: 10.1016/s1047-8477(02)00513-0

Genes

MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12372316-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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