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Article

Early postnatal death and motor disorders in mice congenitally deficient in calnexin expression.

Molecular and cellular biology - 1 Nov 2002

Denzel Angela, Molinari Maurizio, Trigueros Cesar, Martin Joanne E, Velmurgan Shanti, Brown Sue, Stamp Gordon, Owen Michael J

Abstract excerpt

Calnexin is a ubiquitously expressed type I membrane protein which is exclusively localized in the endoplasmic reticulum (ER). In mammalian cells, calnexin functions as a chaperone molecule and plays a key role in glycoprotein folding and quality control within the ER by interacting with folding intermediates via their monoglucosylated glycans. In order to gain more insight into the physiological roles of...

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Identifiers

PMID: 12370287
DOI: 10.1128/MCB.22.21.7398-7404.2002
PMCID: PMC135653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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