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Article

Calnexin family members as modulators of genetic diseases.

Seminars in cell & developmental biology - 1 Oct 1999

Chevet E, Jakob C A, Thomas D Y, Bergeron J J

Abstract excerpt

The endoplasmic reticulum (ER) is an intracellular compartment devoted to the synthesis, segregation and folding of soluble and membrane secretory proteins. Some mutations in these proteins lead to their incorrect or incomplete folding in the ER. The ER has a quality control system which detects misfolded proteins and then specifies their fate. Some mutated proteins are retained in the ER wherein they accumulate...

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Source

Identifiers

PMID: 10597630
DOI: 10.1006/scdb.1999.0316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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