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Article

sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4.

Journal of bacteriology - 1 Oct 2002

Horsburgh Malcolm J, Aish Joanne L, White Ian J, Shaw Les, Lithgow James K, Foster Simon J

Abstract excerpt

The accessory sigma factor sigmaB controls a general stress response that is thought to be important for Staphylococcus aureus survival and may contribute to virulence. The strain of choice for genetic studies, 8325-4, carries a small deletion in rsbU, which encodes a positive regulator of sigmaB activity. Consequently, to enable the role of sigmaB in virulence to be addressed, we constructed an rsbU(+)...

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Identifiers

PMID: 12218034
DOI: 10.1128/JB.184.19.5457-5467.2002
PMCID: PMC135357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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