Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number.

Proceedings of the National Academy of Sciences of the United States of America - 15 Oct 2002

Schnell Eric, Sizemore Max, Karimzadegan Siavash, Chen Lu, Bredt David S, Nicoll Roger A

Abstract excerpt

Excitatory synapses in the brain exhibit a remarkable degree of functional plasticity, which largely reflects changes in the number of synaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs). However, mechanisms involved in recruiting AMPARs to synapses are unknown. Here we use hippocampal slice cultures and biolistic gene transfections to study the targeting of AMPARs to synapses. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium Channels
Share to Disks Large Homolog 4 Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hippocampus

Share to In Vitro Techniques

Share to Intracellular Signaling Peptides and Proteins

Share to Receptors, AMPA

Share to Synapses

Share to Synaptic Transmission

Source

Open in PubMed Open full text

Identifiers

PMID: 12359873
DOI: 10.1073/pnas.172511199
PMCID: PMC129795

Genes

PSD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number.PMID 12359873Read ↗

Phosphorylation of stargazin by protein kinase A regulates its interaction with PSD-95.Semantic proximity Read ↗

The role of transmembrane AMPA receptor regulatory proteins (TARPs) in neurotransmission and receptor trafficking (Review).Semantic proximity Read ↗

Stargazin interacts functionally with the AMPA receptor glutamate-binding module.Semantic proximity Read ↗

TARP γ-7 selectively enhances synaptic expression of calcium-permeable AMPARs.Semantic proximity Read ↗

Distinct domains within PSD-95 mediate synaptic incorporation, stabilization, and activity-dependent trafficking.Semantic proximity Read ↗

Roles of stargazin and phosphorylation in the control of AMPA receptor subcellular distribution.Semantic proximity Read ↗

Selective loss of AMPA receptor subunits at inhibitory neuron synapses in the cerebellum of the ataxic stargazer mouse.Semantic proximity Read ↗

Microtubule-associated protein light chain 2 is a stargazin-AMPA receptor complex-interacting protein in vivo.Semantic proximity Read ↗

Critical postsynaptic density 95/disc large/zonula occludens-1 interactions by glutamate receptor 1 (GluR1) and GluR2 required at different subcellular sites.Semantic proximity Read ↗

Selective loss of AMPA receptors at corticothalamic synapses in the epileptic stargazer mouse.Semantic proximity Read ↗

Two mutations preventing PDZ-protein interactions of GluR1 have opposite effects on synaptic plasticity.Semantic proximity Read ↗

Release your inhibitions: The cell biology of GABAergic postsynaptic plasticitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.