Article
Fetal RHD genotyping in maternal serum during the first trimester of pregnancy.
British journal of haematology - 1 Oct 2002
Costa Jean-Marc, Giovangrandi Yves, Ernault Pauline, Lohmann Laurence, Nataf Valérie, El Halali Najua, Gautier Evelyne
Abstract excerpt
Fetal RHD genotype determination is useful in the management of sensitized RhD-negative pregnant women. It can be ascertained early during pregnancy by chorionic villus sampling (CVS) or amniocentesis. However, these procedures are invasive, resulting both in an increased risk of fetal loss and in an increased severity of immunization due to fetomaternal haemorrhage. A reliable determination of RHD genotype by...
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