Article
K-ras gene mutation analysis to diagnosis pancreatic adenocarcinoma from endoscopic ultrasound-guided tissue acquisition; a systematic review and meta-analysis.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Feb 2024
Tamura Takashi, Ashida Reiko, Wan Ke, Shimokawa Toshio, Kitano Masayuki
Abstract excerpt
BACKGROUND: Endoscopic ultrasound-guided tissue acquisition (EUS-TA) has high sensitivity for the pathological diagnosis of pancreatic masses, but also a high false-negative rate. K-ras gene mutations occur in over 75 % of pancreatic ductal adenocarcinomas (PDAC), and this meta-analysis evaluated the utility of detecting K-ras gene mutations from EUS-TA specimens for the diagnosis of PDAC. METHODS: Relevant...
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