Article
Detection of KRAS gene mutations in endoscopic ultrasound-guided fine-needle aspiration biopsy for improving pancreatic cancer diagnosis.
The American journal of gastroenterology - 1 Dec 2011
Wang Xiaowei, Gao Jun, Ren Yan, Gu Junjun, Du Yiqi, Chen Jie, Jin Zhendong, Zhan Xianbao, Li ZhaoShen, Huang Haojie, Lv ShunLi, Gong Yanfang
Abstract excerpt
OBJECTIVES: Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) is a useful tool in the diagnosis of pancreatic masses. Genetic analysis of these samples could increase the sensitivity and specificity of diagnosis. This study aimed to evaluate the usefulness of a novel method for the detection of mutations in the KRAS (Kirsten rat sarcoma-2 virus) gene for the diagnosis of pancreatic cancer....
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