Article
Analysis of the antimalarial drug resistance protein Pfcrt expressed in yeast.
The Journal of biological chemistry - 20 Dec 2002
Zhang Hanbang, Howard Ellen M, Roepe Paul D
Abstract excerpt
Mutations in the novel membrane protein Pfcrt were recently found to be essential for chloroquine resistance (CQR) in Plasmodium falciparum, the parasite responsible for most lethal human malaria (Fidock, D. A., Nomura, T., Talley, A. K., Cooper, R. A., Dzekunov, S. M., Ferdig, M. T., Ursos, L. M., Sidhu, A. B., Naude, B., Deitsch, K. W., Su, X. Z., Wootton, J. C., Roepe, P. D., and Wellems, T. E. (2000) Mol....
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