Article
Analysis of thrombomodulin gene polymorphism in women with severe early-onset preeclampsia.
Seminars in thrombosis and hemostasis - 1 Jan 1999
Nakabayashi M, Yamamoto S, Suzuki K
Abstract excerpt
The existence of two types of thrombomodulin (TM) amino acid dimorphism (Ala 455 or Val 455) for the development of unexplained thrombophilia is controversial. We have identified the Val 455-TM allele in one patient with severe preeclampsia and the Ala 455-TM allele in another patient with the same disease. We evaluated distributions of the two types of alleles among 20 normal pregnant women and 18 patients with...
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