Article
Candidate gene approach for pharmacogenetic studies.
Pharmacogenomics - 1 Jan 2002
Ring Huijun Z, Kroetz Deanna L
Abstract excerpt
Genetic diversity in the form of single nucleotide DNA polymorphisms (SNPs) contributes to variable disease susceptibility and drug response. The candidate gene approach has been widely used to identify the genetic basis for pharmacogenetic traits and becomes increasingly more powerful with the recent advances in genomic technologies. High-throughput sequencing and SNP genotyping technologies allow the study of...
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