Article
The positive regulator, TraJ, of the Escherichia coli F plasmid is unstable in a cpxA* background.
Journal of bacteriology - 1 Oct 2002
Gubbins Michael J, Lau Isabella, Will William R, Manchak Janet M, Raivio Tracy L, Frost Laura S
Abstract excerpt
The Cpx (conjugative plasmid expression) stress response of Escherichia coli is induced in response to extracytoplasmic signals generated in the cell envelope, such as misfolded proteins in the periplasm. Detection of stress is mediated by the membrane-bound histidine kinase, CpxA. Signaling of the response regulator CpxR by activated CpxA results in the expression of several factors required for responding to...
Topics
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Conjugation, Genetic
- Escherichia coli
- Escherichia coli Proteins
- F Factor
- Gene Expression Regulation, Bacterial
- Mutation
- Protein Kinases
- Signal Transduction
- Transcription, Genetic
