Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The positive regulator, TraJ, of the Escherichia coli F plasmid is unstable in a cpxA* background.

Journal of bacteriology - 1 Oct 2002

Gubbins Michael J, Lau Isabella, Will William R, Manchak Janet M, Raivio Tracy L, Frost Laura S

Abstract excerpt

The Cpx (conjugative plasmid expression) stress response of Escherichia coli is induced in response to extracytoplasmic signals generated in the cell envelope, such as misfolded proteins in the periplasm. Detection of stress is mediated by the membrane-bound histidine kinase, CpxA. Signaling of the response regulator CpxR by activated CpxA results in the expression of several factors required for responding to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Outer Membrane Proteins
Share to Conjugation, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Escherichia coli Proteins

Share to F Factor

Share to Gene Expression Regulation, Bacterial

Share to Protein Kinases

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 12270837
DOI: 10.1128/JB.184.20.5781-5788.2002
PMCID: PMC139618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The positive regulator, TraJ, of the Escherichia coli F plasmid is unstable in a cpxA* background.PMID 12270837Read ↗

Transduction of envelope stress in Escherichia coli by the Cpx two-component system.Semantic proximity Read ↗

A rapid screen for functional mutants of TraM, an autoregulatory protein required for F conjugation.Semantic proximity Read ↗

Error-prone PCR mutagenesis reveals functional domains of a bacterial transcriptional activator, TraJ.Semantic proximity Read ↗

Regulation of the F plasmid traY promoter in Escherichia coli by host and plasmid factors.Semantic proximity Read ↗

The Cpx two-component signal transduction pathway of Escherichia coli regulates transcription of the gene specifying the stress-inducible periplasmic protease, DegP.Semantic proximity Read ↗

Sequence alterations affecting F plasmid transfer gene expression: a conjugation system dependent on transcription by the RNA polymerase of phage T7.Semantic proximity Read ↗

Role of the two-component regulator CpxAR in the virulence of Salmonella enterica serotype Typhimurium.Semantic proximity Read ↗

The Cpx proteins of Escherichia coli K-12: evidence that cpxA, ecfB, ssd, and eup mutations all identify the same gene.Semantic proximity Read ↗

Cpx two-component signal transduction in Escherichia coli: excessive CpxR-P levels underlie CpxA* phenotypes.Semantic proximity Read ↗

The DNA-binding domain of the Escherichia coli CpxR two-component response regulator is constitutively active and cannot be fully attenuated by fused adjacent heterologous regulatory domains.Semantic proximity Read ↗

TraM of plasmid R1 controls transfer gene expression as an integrated control element in a complex regulatory network.Semantic proximity Read ↗

Activation of the Cpx Envelope Stress Response Down-Regulates Expression of Several Locus of Enterocyte Effacement-Encoded Genes in Enteropathogenic Escherichia coliSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.