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Identification of the Leishmania major proteins LmjF07.0430, LmjF07.0440, and LmjF27.2440 as components of fatty acid synthase II.

Journal of biomedicine & biotechnology - 1 Jan 2009

Gurvitz Aner

Abstract excerpt

Leishmania major causes leishmaniasis and is grouped within the Trypanosomatidae family, which also includes the etiologic agent for African sleeping sickness, Trypanosoma brucei. Previous studies on T. brucei showed that acyl carrier protein (ACP) of mitochondrial fatty acid synthase type 2 (FASII) plays a crucial role in parasite survival. Additionally, 3-oxoacyl-ACP synthase TbKASIII as well as TbHTD2...

Topics

Amino Acid Sequence
Electron Transport Chain Complex Proteins
Enoyl-CoA Hydratase
Fatty Acid Synthase, Type II
Leishmania major
Mitochondrial Proteins
Molecular Sequence Data
Mutation
Phenotype
Protozoan Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Sequence Alignment

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Identifiers

PMID: 20145708
DOI: 10.1155/2009/950864
PMCID: PMC2817374

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