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Article

Alterations in regional brain metabolism in genetic and pharmacological models of reduced NMDA receptor function.

Brain research - 4 Oct 2002

Duncan Gary, Miyamoto Seiya, Gu Hongbin, Lieberman Jeffrey, Koller Beverly, Snouwaert John

Abstract excerpt

A mouse line has been developed that expresses low levels of the NMDA R1 (NR1) subunit of the NMDA receptor [Cell 98 (1999) 427]. These NR1 hypomorphic mice represent an experimental model of reduced NMDA receptor function that may be relevant to the pathophysiology of schizophrenia. To further characterize the neurobiological phenotype resulting from developmental NMDA receptor hypofunction, regional brain...

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Identifiers

PMID: 12270494
DOI: 10.1016/s0006-8993(02)03156-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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