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Article

Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes.

Nature cell biology - 1 Oct 2002

Huang Mei, Qian Feng, Hu Yuanyu, Ang Chengeng, Li Zhong, Wen Zilong

Abstract excerpt

Brahma-related gene 1 (BRG1 ) is a key component of the ATP-dependent chromatin-remodelling SWI2-SNF2 complex and has been implicated in regulating gene expression, cell-cycle control and tumorigenesis. Here we report that BRG1 interacts with signal transducer and activator of transcription 2 (STAT2) - a transcription factor that regulates gene expression mediated by interferon-alpha (IFN-alpha). BRG1 enhances...

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Source

Identifiers

PMID: 12244326
DOI: 10.1038/ncb855

Genes

STAT2
IFI27

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes.PMID 12244326Read ↗

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