Article
Structure of the inhibitory region of troponin by site directed spin labeling electron paramagnetic resonance.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 2002
Brown Louise J, Sale Ken L, Hills Ron, Rouviere Clement, Song Likai, Zhang Xiaojun, Fajer Piotr G
Abstract excerpt
Site-directed spin labeling EPR (SDSL-EPR) was used to determine the structure of the inhibitory region of TnI in the intact cardiac troponin ternary complex. Maeda and collaborators have modeled the inhibitory region of TnI (skeletal 96-112: the structural motif that communicates the Ca(2+) signal to actin) as a kinked alpha-helix [Vassylyev, D., Takeda, S., Wakatsuki, S., Maeda, K. & Maeda, Y. (1998) Proc....
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