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Article

Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia.

The New England journal of medicine - 7 Aug 2008

Rawstron Andy C, Bennett Fiona L, O'Connor Sheila J M, Kwok Marwan, Fenton James A L, Plummer Marieth, de Tute Ruth, Owen Roger G, Richards Stephen J, Jack Andrew S, Hillmen Peter

Abstract excerpt

BACKGROUND: A diagnosis of chronic lymphocytic leukemia (CLL) requires a count of over 5000 circulating CLL-phenotype cells per cubic millimeter. Asymptomatic persons with fewer CLL-phenotype cells have monoclonal B-cell lymphocytosis (MBL). The goal of this study was to investigate the relation between MBL and CLL. METHODS: We investigated 1520 subjects who were 62 to 80 years of age with a normal blood count...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18687638
DOI: 10.1056/NEJMoa075290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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