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Article

Amplification of the androgen receptor gene in bone metastases from hormone‐refractory prostate cancer

17 Sept 2002

Abstract excerpt

The aim of this study was to examine the prevalence of androgen receptor (AR) amplification in metastases to bone and other sites in patients with hormone-refractory prostate cancer (HRPC) and to compare these findings with those in pretreatment primary tumour samples from the same patients. Tissue from 24 patients with HRPC was available for study, together with 13 primary tumour specimens. AR gene amplification...

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PMID: 12237884
DOI: 10.1002/path.1206

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