Article
Collagen gene polymorphisms influence fracture risk and bone mass acquisition during childhood and adolescent growth.
Bone - 1 Nov 2010
Blades H Z, Arundel P, Carlino W A, Dalton A, Crook J S, Freeman J V, Bishop N J
Abstract excerpt
Fractures are common in childhood with incidence maximal during puberty, around the time of peak height velocity. The relationships between single nucleotide polymorphisms (SNPs) in COL1A1 and COL1A2, bone mass acquisition, and childhood fractures are unclear. We recruited 394 children and adolescents aged 4 to 16 years into a noninterventional case control study. All had suffered an episode of trauma leading to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.