Article
Association between the low molecular weight cytosolic acid phosphatase gene ACP1*A and comorbid features of Tourette syndrome.
Neuroscience letters - 20 Sept 2002
Bottini Nunzio, MacMurray James, Rostamkani Masoud, McGue Matt, Iacono William G, Comings David E
Abstract excerpt
Protein tyrosine phosphatases have been implicated in the regulation of serotonergic and dopaminergic activity in the central nervous system. In a recent study we found that nonA/nonA homozygosity at the locus codifying for the low molecular weight protein tyrosine phosphatase (ACP1) was associated with increased rates of major depression in males (P<0.00003), suggesting that the ACP1*A single nucleotide...
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