Article
Convulsive disorder and the genetics of signal transduction; a study of a low molecular weight protein tyrosine phosphatase in a pediatric sample.
Neuroscience letters - 29 Nov 2002
Bottini Nunzio, Saccucci Patrizia, Piciullo Antonella, Iannetti Paola, Lucarini Nazareno, Lucarelli Paola, Gloria-Bottini Fulvia, Curatolo Paolo
Abstract excerpt
Recent studies point to an involvement of kinases and phosphatases in ionic channel regulation and in physiopathologic mechanisms leading to convulsive disorders. Acid phosphatase locus 1 (ACP1), also named cytosolic low molecular weight phosphotyrosine phosphatase, is a highly polymorphic phosphatase that is especially abundant in the central nervous system and is known to be involved in several signal...
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